Computational Biology and Bioinformatics

Volume 1, Issue 2, April 2013

  • Modeling the Mitogen Activated Protein (MAP)-Kinase Pathway Using Ordinary Differential Equations

    Sharadwata Pan, Sameer E. Mhatre

    Issue: Volume 1, Issue 2, April 2013
    Pages: 6-9
    Received: Apr. 30, 2013
    Accepted:
    Published: Jun. 10, 2013
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    Abstract: Mitogen Activated Protein (MAP) Kinase pathway is central to comprehend the key cellular signal transduction mechanisms in animal physiology, including human beings. Modeling MAP Kinase pathway has two main applications: deciphering a transient response of three main components (MAPKKK, MAPKK and MAPK) to regulate signaling and utilizing the models... Show More