Computational Biology and Bioinformatics

Volume 3, Issue 4, August 2015

  • Molecular Docking Interaction of Mycobacterium Tuberculosis LipB Enzyme with Isoniazid, Pyrazinamide and a Structurally Altered Drug 2, 6 Dimethoxyisonicotinohydrazide

    Muthuraman Namasivayam, Suresh Ramraj Subashchandrabose

    Issue: Volume 3, Issue 4, August 2015
    Pages: 45-51
    Received: Jul. 08, 2015
    Accepted: Jul. 18, 2015
    Published: Jul. 28, 2015
    Downloads:
    Views:
    Abstract: Tuberculosis is an infectious airborne disease caused by a bacterial infection that affects the lungs and other parts of the body. Vaccination against tuberculosis is available but proved to be unsuccessful against emerging multi drug and extensive drug resistant bacterial strains. This in turn raises the pressure to speed up the research on develo... Show More
  • Novel Computerized Approaches to Investigating Pharmacological Activities

    Nwankwo Norbert, Godwin Molokwu, Ngozika Njoku

    Issue: Volume 3, Issue 4, August 2015
    Pages: 52-64
    Received: May 16, 2015
    Accepted: May 26, 2015
    Published: Aug. 01, 2015
    Downloads:
    Views:
    Abstract: Complementing clinical assessments using computerized procedures with the view of completely disengaging from clinical procedures may become inevitable in future. Huge biological and pharmacological data (such as sequences) are churned out daily such that it is becoming difficult to process them without the aid of computers. Computerized approaches... Show More