Computational Biology and Bioinformatics

Volume 2, Issue 1, February 2014

  • Genetic Proclivities of Two-Component Modulated Aerobiosis

    Hamzat Ibiyeye Tijani, Idris Abdulrahman, Bashir Mohammed Abubakar, Sulaiman Mohammed, Jibrin Ndejiko Mohammed, Haruna Saidu, Hindatu Yusuf

    Issue: Volume 2, Issue 1, February 2014
    Pages: 1-6
    Received: Dec. 11, 2013
    Accepted:
    Published: Jan. 10, 2014
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    Abstract: Great advances have been made in the past five decades in understanding the molecular mechanics of the two-component signal transduction pathway in bacteria but its applications in Medicine and Food Industries are yet to be fully unravelled. We discuss the varying changes in the extracellular environment of bacteria and their possession of multiple... Show More
  • Uncertainty Quantification Driven Predictive Multi-Scale Model for Synthesis of Mycotoxins

    Sourav Banerjee, Gabriel Terejanu, Anindya Chanda

    Issue: Volume 2, Issue 1, February 2014
    Pages: 7-12
    Received: Jan. 03, 2014
    Accepted:
    Published: Jan. 30, 2014
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    Abstract: Many toxic molds synthesize and release an array of poisons, termed mycotoxins that have an enormous impact on human health, agriculture and economy [1]. These molds contaminate our buildings, indoor air and crops, cause life threatening human and animal diseases and reduce agricultural output [2]. In order to design appropriate approaches to minim... Show More
  • Computational Design of Peptide Vaccine against Acinetobacter Baumannii Infection using Comparative Genomic Approach

    Ajao Abdullahi Taiwo, Ajao Jumoke Falilat, Yakubu Sabo Ezemuel

    Issue: Volume 2, Issue 1, February 2014
    Pages: 13-18
    Received: Jan. 12, 2014
    Accepted:
    Published: Mar. 10, 2014
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    Abstract: The bacterial species Acinetobacter baumannii is a major cause of hospital acquired infection throughout the world and it is increasing public health concern. Infection caused by multidrug resistant A. baumannii is currently among the most difficult to treat due to propensity to acquire mobile genetic element. To date there is no vaccine or specifi... Show More