Computational Biology and Bioinformatics

Volume 3, Issue 6, December 2015

  • Input Dataset Survey of In-Silico Tools for Inference and Visualization of Gene Regulatory Networks (GRN)

    Taiwo Adigun, Angela Makolo, Segun Fatumo

    Issue: Volume 3, Issue 6, December 2015
    Pages: 81-87
    Received: Sep. 25, 2015
    Accepted: Oct. 04, 2015
    Published: Nov. 16, 2015
    Downloads:
    Views:
    Abstract: Understanding Gene Regulatory Network (GRN) is considered to be the fundamental approach to many biological questions, and the input dataset performs a crucial role in investigating and visualizing the gene regulatory network [5, 14, 17, 23, 34, 37, 40, 41, 44, 45]. Several software tools [2, 5, 7, 10, 11, 14, 21, 22, 25, 31-33, 37, 38, 40, 41, 44]... Show More
  • Methods for Evaluating Agglomerative Hierarchical Clustering for Gene Expression Data: A Comparative Study

    Md. Bipul Hossen, Md. Siraj-Ud-Doulah, Aminul Hoque

    Issue: Volume 3, Issue 6, December 2015
    Pages: 88-94
    Received: Dec. 05, 2015
    Accepted: Dec. 14, 2015
    Published: Dec. 30, 2015
    Downloads:
    Views:
    Abstract: Microarray is already well established techniques to understand various cellular functions by profiling transcriptomics data. To capture the overall feature of high dimensional variable datasets in microarray data, various analytical and statistical approaches are already developed. One of the most widely used Agglomerative Hierarchical Clustering ... Show More