Computational Biology and Bioinformatics

Volume 6, Issue 2, December 2018

  • Prediction of Escherichia Coli K-12 Promoters Using Convolutional Neural Network

    Lu Wang, Ping Wan

    Issue: Volume 6, Issue 2, December 2018
    Pages: 31-35
    Received: Oct. 11, 2018
    Accepted: Oct. 31, 2018
    Published: Nov. 30, 2018
    DOI: 10.11648/j.cbb.20180602.11
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    Abstract: Promoters are significant cis-acting elements in genomes and play important roles in gene regulation. Each gene is regulated by a specific type of promoter, so determining the type of promoter for regulation of a gene is crucial to explore the gene function. Although some computational methods to predict promoters have been proposed, their performa... Show More
  • Docking Studies for Assessment of Wound Healing Potential of Dalethyne Derivatives: An in Silico Approach

    Kayapan Satya Dharshan

    Issue: Volume 6, Issue 2, December 2018
    Pages: 36-51
    Received: Oct. 01, 2018
    Accepted: Nov. 19, 2018
    Published: Dec. 18, 2018
    DOI: 10.11648/j.cbb.20180602.12
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    Abstract: Background: A cascade of enzymes acting in union is involved in the natural wound healing pharmacology of humans making the process a lengthy one. This in turns necessitates new synthetic molecules effective in accelerating the wound healing process. Objective: The present work deals with synthetic molecules aimed at healing wounds targeting the es... Show More