Computational Biology and Bioinformatics

Volume 10, Issue 2, December 2022

  • Computational Studies and Scaffold Search for APOE4 as Coronary Artery Disease Target by Virtual Screening

    Lima Hazarika, Supriyo Sen, Jitesh Doshi

    Issue: Volume 10, Issue 2, December 2022
    Pages: 49-59
    Received: 17 July 2022
    Accepted: 4 August 2022
    Published: 17 August 2022
    Abstract: Apolipoprotein E (APOE) polymorphism is involved in the pathogenesis of atherosclerosis and conveys a higher risk of coronary artery disease (CAD). The structural features of the isoforms (APOE2, APOE3, and APOE4) differ by only single amino acid that explicate their unique functions as lipid transporter with a role in cholesterol metabolism. It is... Show More
  • Citizen Science: A Significant Contribution to Biodiversity Monitoring and Conservation

    Muzafar Riyaz

    Issue: Volume 10, Issue 2, December 2022
    Pages: 60-67
    Received: 15 July 2022
    Accepted: 29 July 2022
    Published: 24 August 2022
    Abstract: The term "biodiversity" refers to the diverse variety of living things that exist in our natural environment including not just plants and animals, but also fungi and even microscopic organisms such as bacteria. Since there are still millions of species that have not been identified, the overall biodiversity of our world is immense. The biodiversit... Show More
  • Age in Impacting the Occurrence of Chronic Diseases: Case of Recurrently Diagnosed Diseases at Korhogo Regional Hospital in Northern of Cote d’Ivoire

    Dago Dougba Noel, Daramcoum Wentoin Alimata Marie-Pierre, Dagnogo Olefongo, Kouadio Kouassi Joel, Kimou Adjiman Florent

    Issue: Volume 10, Issue 2, December 2022
    Pages: 68-79
    Received: 3 October 2022
    Accepted: 26 October 2022
    Published: 15 December 2022
    Abstract: Background: Our previous study suggested Korhogo district as strongly influenced by parasitical and infectious diseases and as well high blood pressure (HBP) troubles. In the same study, we shown that recurrently diagnosed diseases at Korhogo Regional Hospital (KRH) clustered in two group, depending on the regular and/or irregular dynamism of their... Show More