Computational Biology and Bioinformatics

Volume 3, Issue 1, February 2015

  • Protein Function Prediction Using Neighbor Counting with Dynamic Threshold from Protein-Protein Interaction Network

    Md. Khaled Ben Islam, Julia Rahman, Md. Al Mehedi Hasan, Mohammed Nasser

    Issue: Volume 3, Issue 1, February 2015
    Pages: 1-5
    Received: Jan. 10, 2015
    Accepted: Jan. 26, 2015
    Published: Feb. 02, 2015
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    Abstract: In recent years, a large number of proteins of different organisms have been discovered but due to high experimental cost and uncertain time boundary, yet it is not possible to find out all of the functionalities of those proteins. With the recent advent of huge protein-protein interactions, it becomes an opportunity to computationally predict a pr... Show More
  • In-Silico Evaluation of the Capsid Proteins of FMDV as Potential Vaccine Candidates

    F. M. N. Hassan, Md. Shaifur Rahman, K. M. T. Rahman, Sharmin S. Sumi, Md. F. Islam, Md. Badrul Alam, Md. Giasuddin, Khondoker M. Hossain

    Issue: Volume 3, Issue 1, February 2015
    Pages: 6-20
    Received: Nov. 23, 2014
    Accepted: Mar. 02, 2015
    Published: Mar. 09, 2015
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    Abstract: In this study, the capsid proteins of four major serotypes of Foot and Mouth Disease Virus (FMDV) were assessed as the vaccine candidates. Different protein sequences regarding FMDV capsid of O, A, Asia 1 and C type were identified from NCBI Genome Database and UniprotKB. Phylogenetic tree of the four serotypes was developed using ClustalW software... Show More