Computational Biology and Bioinformatics

Volume 7, Issue 1, June 2019

  • Transcription Direction Patterns of Adjacent Genes in Mycobacterium Tuberculosis Using GENAVIS

    Angela Uche Makolo

    Issue: Volume 7, Issue 1, June 2019
    Pages: 1-4
    Received: Feb. 02, 2019
    Accepted: Mar. 22, 2019
    Published: Apr. 18, 2019
    Abstract: The understanding of the relationship of a gene with other genes in its neighbourhood and the implication of this relationship on the biochemical activities of the entire genome need an efficient computational tool to unfold the relationship. GENAVIS: (GENe Adjacency VIsualization Software) is an open source, platform independent web-based software... Show More
  • Prediction of Single Nucleotide Polymorphisms in TNFSF4 and Confirmation of Its Relationship with AITD and SLE: Bioinformatics Approach

    Sevgi Kalkanli Tas, Eylem Cagiltay, Duygu Kirkik, Nevin Kalkanli

    Issue: Volume 7, Issue 1, June 2019
    Pages: 5-10
    Received: Jun. 27, 2019
    Accepted: Jul. 17, 2019
    Published: Jul. 30, 2019
    Abstract: Tumor Necrosis Factor Ligand Superfamily Member4 (TNFSF4) has a huge family of physically homologous transmembrane proteins that regulate various functions in responding cells containing proliferation, differentiation, apoptosis, and inflammatory gene expression. TNFSF4 can play significant role in inflammatory diseases that its polymorphisms of th... Show More